It's worth considering rehoming but there might be other options. For one, not letting them get out into your bedroom and most definitely not on your bed. Having a separate playpen for roaming time could help and more thorough sanitization. It could also not be the rats, paper bedding can be dusty and affect air quality, depending on what brand you're using. But, if you do decide to get rid of them, which is valid, definitely make sure their new home is suitable<3